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Rabbit Anti-Mouse IgM/HRP bs-0368R-HRP

辣根过氧化物酶标记的兔抗小鼠IgM

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产品编号bs-0368R-HRP
英文名称Rabbit Anti-Mouse IgM / HRP
中文名称辣根过氧化物酶标记的兔抗小鼠IgM
别    名Rabbit Anti-Mouse IgM (HRP); Immunoglobulin M;   
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Mouse
产品应用WB=1:1000-10000, IHC-P=1:100-500, IHC-F=1:100-1000, ELISA=1:1000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
性    状Liquid
浓    度2.0 mg/ml
免 疫 原Native Mouse IgM 
亚    型IgG
纯化方法affinity purified by Protein A
缓 冲 液10 mM TBS (pH=7.4) with 1% BSA, 0.03% Proclin300 and 50% glycerol.
保存条件Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍IgM normally constitutes about 10% of serum immunoglobulins. IgM antibody is prominent in early immune responses to most antigens and is largely confined to plasma due to it's large size. Monomeric IgM is expressed as a membrane bound antibody on the surface of B cells and as a pentamer when secreted by plasma cells. Due to it's high valency IgM is more efficient than other isotypes is binding antigens with repeating epitopes (virus particles and red blood cells) and is more efficient than IgG in activiating the complement pathway. The gene for the mu constant region contains four domains separated by short intervening sequences.


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