英文名称：ROD1/PTBP3

中文名称：调节分化蛋白ROD1抗体

别    名：DKFZp781I1117; Fission yeast differentiation regulator; OTTHUMP00000021931; OTTHUMP00000021932; Polypyrimidine tract binding protein 3; regulator of differentiation 1; Regulator of differentiation (in S. pombe) 1; Regulator of differentiation 1; ROD 1; Rod1; ROD1 regulator of differentiation 1; ROD1_HUMAN.  

抗体来源：Rabbit

克隆类型：Polyclonal

交叉反应：Mouse, Rat,  (predicted: Human, Dog, Pig, Cow, Horse, Rabbit, Zebrafish, Sheep, )

产品应用：WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

理论分子量：60kDa

细胞定位：细胞核 

性    状：Liquid

浓    度：1mg/ml

免 疫 原：KLH conjugated synthetic peptide derived from human ROD1/PTBP3: 201-300/552 

亚    型：IgG

纯化方法：affinity purified by Protein A

缓 冲 液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件：Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

注意事项：This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

产品介绍：

The protein encoded by this gene binds RNA and is a regulator of cell differentiation. The encoded protein preferentially binds to poly(G) and poly(U) sequences in vitro. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]

Function:

RNA-binding protein that mediates pre-mRNA alternative splicing regulation. Plays a role in the regulation of cell proliferation, differentiation and migration. Positive regulator of EPO-dependent erythropoiesis. Participates in cell differentiation regulation by repressing tissue-specific exons. Promotes FAS exon 6 skipping. Binds RNA, preferentially to both poly(G) and poly(U).

Subcellular Location:

Contains 4 RRM (RNA recognition motif) domains.

Tissue Specificity:

Expressed in several hematopoietic cell lines examined.

Similarity:

Contains 4 RRM (RNA recognition motif) domains.