Goat Anti-Chicken IgY

Quantity size:

1mg  10mg  

Background:

In chickens, immunoglobulin Y is the functional equivalent to Immunoglobulin G(IgG). Like IgG, it is composed of two light and two heavy chains. Structurally, thesetwo types of immunoglobulin differ primarily in the heavy chains, which in IgY havea molecular mass of about 65,100 atomic mass units (amu), and are thus largerthan in IgG. The light chains in IgY, with a molar mass of about 18,700 amu, aresomewhat smaller than the light chains in IgG. The molar mass of IgY thus amountsto about 167,000 amu. The steric flexibility of the IgY molecule is less than that ofIgG.Functionally, IgY is partially comparable to Immunoglobulin E (IgE), as well asto IgG. However, in contrast to IgG, IgY does not bind to Protein A, to Protein G,or to cellular Fc receptors. Furthermore, IgY does not activate the complementsystem. The name Immunoglobulin Y was suggested in 1969 by G.A. Leslie andL.W. Clem, after they were able to show differences between the immunoglobulinsfound in chicken eggs, and immunoglobulin G. Other synonymous names areChicken IgG, Egg Yolk IgG, and 7S-IgG.

Application:

ELISA=1:5000-10000, Use at an assay dependent dilution.

Not yet tested in other applications.

Optimal working dilutions must be determined by the end user.

Storage:

 Store at -20℃ stable for 2 years (lyophilized powder). Avoid repeated freeze/thaw cycles.

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