Anti-IRS3/AF647

Quantity size:

100ul

Concentration:

1mg/ml  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

The family of insulin receptor substrates (IRSs) has been reported to play important roles for signal transduction of various hormones. Four members of the IRS family have been described. Each IRS is believed to have different functions; however, the distinct physiological roles of each IRS are unclear. IRS-1 may mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2.

Also known as:

IRS1--Insulin receptor substrate-3; IRS3; IRS-3; IRS3.

Specificity:

Rabbit Polyclonal IgG, affinity purified by Protein A.

Reacts with: Mouse, Rat, Pig, .

Immunogen: KLH conjugated synthetic peptide derived from mouse IRS-3.

Predicted Molecular Weight: 53kDa.

Storage:

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

Application:

IF=1:50-200  

Excitation spectrum: 647nm
Emission spectrum: 666nm
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.

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